Resveratrol protects the brain of obese mice from oxidative damage
Resveratrol (3, 5, 4′‐trihydroxy‐trans‐stilbene) is a polyphenolic phytoalexin that exerts
cardioprotective, neuroprotective, and antioxidant effects. Recently it has been shown that
obesity is associated with an increase in cerebral oxidative stress levels, which may
enhance neurodegeneration. The present study evaluates the neuroprotective action of
resveratrol in brain of obese (ob/ob) mice. Resveratrol was administered orally at the dose of
25 mg kg− 1 body weight daily for three weeks to lean and obese mice. Resveratrol had no …
cardioprotective, neuroprotective, and antioxidant effects. Recently it has been shown that
obesity is associated with an increase in cerebral oxidative stress levels, which may
enhance neurodegeneration. The present study evaluates the neuroprotective action of
resveratrol in brain of obese (ob/ob) mice. Resveratrol was administered orally at the dose of
25 mg kg− 1 body weight daily for three weeks to lean and obese mice. Resveratrol had no …
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