Retinoblastoma: recent trends in diagnosis and management
AM Rusakevich, AC Schefler - Current Surgery Reports, 2022 - Springer
Current Surgery Reports, 2022•Springer
Abstract Purpose of Review The following review outlines the current approaches used in
the diagnosis and management of retinoblastoma, emphasizing new findings in the field of
genomic analysis. Recent Findings Recent genomic studies of retinoblastoma have
demonstrated that molecular markers from aqueous humor samples correlate with disease
progression and have also identified novel copy number alterations associated with more
aggressive disease. Consideration of these genomic factors may be warranted in future …
the diagnosis and management of retinoblastoma, emphasizing new findings in the field of
genomic analysis. Recent Findings Recent genomic studies of retinoblastoma have
demonstrated that molecular markers from aqueous humor samples correlate with disease
progression and have also identified novel copy number alterations associated with more
aggressive disease. Consideration of these genomic factors may be warranted in future …
Purpose of Review
The following review outlines the current approaches used in the diagnosis and management of retinoblastoma, emphasizing new findings in the field of genomic analysis.
Recent Findings
Recent genomic studies of retinoblastoma have demonstrated that molecular markers from aqueous humor samples correlate with disease progression and have also identified novel copy number alterations associated with more aggressive disease. Consideration of these genomic factors may be warranted in future management of retinoblastoma.
Summary
Retinoblastoma is a curable childhood cancer with optimal management that is particularly available in the developed world. Recent advancements in genomic monitoring and validation of approaches to augment international care offer hope for a concrete path toward improving global survival.
Springer
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