Dental implants are one of the most successful treatment choices for edentulous areas. The surgical and rehabilitation phases of dental implant surgery are greatly affected by the history and clinical examination of the patient. Surgical procedure for dental implant requires minimal trauma and circumvent excessive bleeding and stress. Hence; we planned the present study to assess the success of dental implants in patients with medically compromised status. This retrospective study included assessment of the files of the patients selected for study was grouped into Study group and Control group. Study group consisted of medically compromised patients whereas control group consisted of normal healthy patients. Patient’s age, gender and ASA status were studied for demographic profile. The collection of data for the study was done after obtaining ethical clearance from the ethical committee of the institute. The statistical analysis of the data was done using t test and chi square test by SPSS software. We included a total of 100 patients. 50 patients belonged to the study group, while the remaining 50 belonged to the control group. In the control group, dental implant failure occurred in a single patient while in the study group, dental implant failure occurred in 3 patients. Removal of dental implants occurred in 10 patients of control group; while it was done in 9 patients of the study group. Similar rate of success occurs in medically compromised patients.