Increased environmental awareness and depletion of fossil petroleum resources are driving the automotive industry to seek out and use alternative fuels. For instance, the biofuel is a major renewable energy source to supplement declining fossil fuel resources. In particular, alcohols are an important category of biofuels, bio-ethanol and bio-methanol being a feasible alternative to gasoline. A very important thing is that alcohols use does not require major spark ignition engine (SIE) modifications. This review paper covers the potential of alcohols from biomass as alternative fuels for automotive SIE application. The presented literature review focused mainly on the relative advantages and drawbacks of these alternative fuels for application to internal combustion engine (ICE).