[PDF][PDF] Risk factors of obstructive sleep apnea syndrome in obese early adolescents: a prediction model using scoring system

B Supriyatno, M Said, B Hermani, DR Sjarif… - Paediatric Respiratory …, 2010 - academia.edu
B Supriyatno, M Said, B Hermani, DR Sjarif, S Sastroasmoro
Paediatric Respiratory Reviews, 2010academia.edu
Aim: to obtain the OSAS prevalence and risk factors of OSAS in obese early adolescents
and to create a scoring system based on risk factors for diagnosing OSAS. Methods: an
observational study in Jakarta, November 2007 until December 2008 on obese adolescents
aged 10-12 years with snoring. Subjects underwent clinical examination, lung function test,
paranasal sinus X-ray, and polisomnography. Measured outcomes were diagnosis of OSAS;
sensitivity, specificity, predictive values, and likelihood ratios of a scoring system based on …
Aim
to obtain the OSAS prevalence and risk factors of OSAS in obese early adolescents and to create a scoring system based on risk factors for diagnosing OSAS.
Methods
an observational study in Jakarta, November 2007 until December 2008 on obese adolescents aged 10-12 years with snoring. Subjects underwent clinical examination, lung function test, paranasal sinus X-ray, and polisomnography. Measured outcomes were diagnosis of OSAS; sensitivity, specificity, predictive values, and likelihood ratios of a scoring system based on risk factors.
Results
the prevalence of OSAS in obese early adolescents is 38.2% using AHI cut-off point of> 3 on PSG. Tonsillar hypertrophy, adenoid hypertrophy, and neck circumference were the main risk factors. Scoring system was designed based on these results: OS= T+ A+ NC; OS= OSAS score; T= tonsil hypertrophy (> T3 scored 1,< T3 scored 0); A= adenoid hypertrophy (adenoid and nasopharynx ratio of> 0.8 scored 1.5,< 0.8 scored 0); NC= neck circumference (> 34 cm scored 1;< 34 cm scored 0). Children were most likely to have OSAS if they had a total score of 3.5. This scoring system has a sensitivity of 62%(95% CI 47 to 77%), specificity 100%(95% CI 100 to 100%), positive predictive value 100%(95% CI 100 to 100%), negative predictive value 81%(95% CI 73 to 89%), unlimited LR (+), LR (-) of 0.38 (CI 95% 0.6 to 0.56).
Conclusion
a scoring system based on tonsillar hypertrophy, adenoid hypertrophy, and neck circumference has sensitivity and specificity of 62% and 100% in diagnosing OSAS.
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