Risk of prostate cancer in men treated with -reductase inhibitors—a large population-based prospective study

A Wallerstedt, P Strom, H Gronberg… - … the National Cancer …, 2018 - academic.oup.com
… any alteration in prostate cancer risk for men treated in a clinical … done in the largest prospective
population-based cohort of men … patterns, PSA levels, and prostate cancer diagnostics. …

-reductase inhibitors and the risk of cancer-related mortality in men with prostate cancer

L Azoulay, M Eberg, S Benayoun, M Pollak - JAMA oncology, 2015 - jamanetwork.com
… their safety on prostate cancer incidence, we conducted a large population-based study to …
-ARIs for BPH to treat initial symptoms of yet undiagnosed prostate cancer, and to account for …

Association of -reductase inhibitors with prostate cancer mortality

L Björnebo, T Nordström, A Discacciati… - JAMA …, 2022 - jamanetwork.com
… This large population-based cohort study found a decreased risk of death of prostate cancer
in men treated with 5-ARI for more than 2 years for lower urinary tract symptoms compared …

Use of -reductase inhibitors for lower urinary tract symptoms and risk of prostate cancer in Swedish men: nationwide, population based case-control study

D Robinson, H Garmo, A Bill-Axelson, L Mucci… - Bmj, 2013 - bmj.com
… 5-ARI use and high grade prostate cancer. The aim of … treating lower urinary tract symptoms
due to prostatic enlargement in a clinical setting and prostate cancer risk, in particular cancer

Association of treatment with -reductase inhibitors with time to diagnosis and mortality in prostate cancer

RR Sarkar, JK Parsons, AK Bryant, ST Ryan… - JAMA internal …, 2019 - jamanetwork.com
… In this large population-based study, we observed that prediagnostic users of 5-ARIs … that
5-ARIs inherently increase the risk of high-grade prostate cancer as suggested by the US Food …

-reductase inhibitors and the risk of bladder cancer in a large, population-based cohort

S Dekalo, E McArthur, J Campbell, M Ordon… - … Oncology: Seminars and …, 2023 - Elsevier
treatment effect, a requirement for a time period of >2 years (based on our results), and potential
… concerns due to the black-box warning that persists regarding high-risk prostate cancer. …

Long-term use of -reductase inhibitors and the risk of male breast cancer

RG Duijnhoven, SMJM Straus, PC Souverein… - Cancer Causes & …, 2014 - Springer
… A history of testicular cancer, prostate cancer and treatment with … large study population,
there was no evidence that men treated with -reductase inhibitors are at an increased risk

-Reductase inhibitors and risk of prostate cancer death

T Bonde Miranda, H Garmo, P Stattin… - The Journal of …, 2020 - auajournals.org
… The -reductase inhibitors finasteride and dutasteride are used to treat lower urinary tract
… Similar findings were observed in a large population based Finnish observational study …

5-α Reductase Inhibitors and Prostate Cancer Mortality

RJ Hamilton, J Chavarriaga, N Khurram… - JAMA Network …, 2024 - jamanetwork.com
… -inhibitors (5-ARIs) are approved for treating benign prostatic hyperplasia (BPH) and have
been found to reduce prostate cancer (PCa) risk … of the largest, population-based cohorts with …

The Cardiovascular Safety of Five-Alpha-Reductase Inhibitors Among Men with Benign Prostatic Hyperplasia: A Population-Based Cohort Study

HT Ayele, P Reynier, L Azoulay, RW Platt… - The American Journal of …, 2023 - Elsevier
… 5αRIs inhibit the -reductase enzyme, resulting in lower levels of … In our large
population-based cohort study, we did not … adjusted for cancers other than prostate cancer and …