Risk of recurrence after discontinuation of antiepileptic drug therapy in children with epilepsy
F Incecik, OM Herguner, S Altunbasak… - Journal of Pediatric …, 2014 - journals.lww.com
Objectives: The numerous antiepileptic drug (AED) withdrawal studies published in the last
40 years have relied mainly on heterogeneous study groups. There is still no general
agreement on the criteria to predict safe discontinuation. The goal of this study was to
assess the outcome of AED withdrawal in epileptic children. Materials and Methods: Three
hundred and eight children with epilepsy were enrolled, and these patients followed at least
1 year after drug withdrawal. Time to seizure relapse and predictive factors were analyzed …
40 years have relied mainly on heterogeneous study groups. There is still no general
agreement on the criteria to predict safe discontinuation. The goal of this study was to
assess the outcome of AED withdrawal in epileptic children. Materials and Methods: Three
hundred and eight children with epilepsy were enrolled, and these patients followed at least
1 year after drug withdrawal. Time to seizure relapse and predictive factors were analyzed …