Role of calcium-phosphate product and bone-associated proteins on vascular calcification in renal failure

M Cozzolino, AS Dusso… - Journal of the American …, 2001 - journals.lww.com
Cardiovascular events are the most frequent cause of death in patients with chronic renal
failure (1–2). Heterotopic calcification of blood vessel walls occurs frequently with advanced
age, atherosclerosis, and diabetes mellitus (3). In chronic renal failure, autopsy (4–5) and
clinical investigations (6) have documented a higher prevalence of coronary plaques in
dialyzed patients compared with the nonuremic population. The risk factors that contribute to
the higher prevalence of atherosclerotic lesions in chronic renal failure include dyslipidemia …
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