Role of nitric oxide on uterine and ovarian prostaglandin synthesis during luteolysis in the rat

AB Motta, AM Franchi, MF Gimeno - Prostaglandins, leukotrienes and …, 1997 - Elsevier
In previous studies in our laboratory, we demonstrated that oxytocin (oxy) augmented
prostaglandin F2α (PGF2α) synthesis via enhancing the uptake of Ca2+ by uterine tissue.
On the other hand, we have shown that oxy enhances PGF2α synthesis in uterine and
ovarian tissues during the corpus luteum (CL) regression in the rat. In the present study we
explore the possible relation between endogenous nitric oxide (NO) and oxy on PGs
synthesis during the luteolytic phase in the rat. The experiments were done in uterine and …
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