Room Temperature, Open-Flask C–P Bond-Formation on Water under Catalyst-Free Conditions

R Choudhary, R Bai, P Singh, MC Sharma… - …, 2018 - thieme-connect.com
R Choudhary, R Bai, P Singh, MC Sharma, SS Badsara
SynOpen, 2018thieme-connect.com
A catalyst-free C–P bond-formation in an open flask at room temperature between isatin
derivatives and phosphorus surrogates on water is described. Isatin derivatives possessing
different substitutes underwent C–P coupling reaction with a variety of phosphine oxides
under the reaction conditions employed, providing the desired products in up to quantitative
yields.
A catalyst-free C–P bond-formation in an open flask at room temperature between isatin derivatives and phosphorus surrogates on water is described. Isatin derivatives possessing different substitutes underwent C–P coupling reaction with a variety of phosphine oxides under the reaction conditions employed, providing the desired products in up to quantitative yields.
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