Round window delivery of dexamethasone ameliorates local and remote hearing loss produced by cochlear implantation into the second turn of the guinea pig …

H Eastwood, A Chang, G Kel, D Sly, R Richardson… - Hearing research, 2010 - Elsevier
Application of dexamethasone to the round window has been shown to ameliorate high
frequency hearing loss resulting from the trauma of cochlear implantation in experimental
animals, but elucidation of the factors influencing protection of the high frequencies has
been confounded by the local trauma from electrode array insertion. In this experiment, a
second turn cochleostomy and implantation was performed on guinea pigs, to examine
protection in the basal turn without the confounding effect of local trauma, as well as to test …
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