SLC27 fatty acid transport proteins
CM Anderson, A Stahl - Molecular aspects of medicine, 2013 - Elsevier
The uptake and metabolism of long chain fatty acids (LCFA) are critical to many
physiological and cellular processes. Aberrant accumulation or depletion of LCFA underlie
the pathology of numerous metabolic diseases. Protein-mediated transport of LCFA has
been proposed as the major mode of LCFA uptake and activation. Several proteins have
been identified to be involved in LCFA uptake. This review focuses on the SLC27 family of
fatty acid transport proteins, also known as FATPs, with an emphasis on the gain-and loss-of …
physiological and cellular processes. Aberrant accumulation or depletion of LCFA underlie
the pathology of numerous metabolic diseases. Protein-mediated transport of LCFA has
been proposed as the major mode of LCFA uptake and activation. Several proteins have
been identified to be involved in LCFA uptake. This review focuses on the SLC27 family of
fatty acid transport proteins, also known as FATPs, with an emphasis on the gain-and loss-of …
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