SOX11 expression correlates to promoter methylation and regulates tumor growth in hematopoietic malignancies

E Gustavsson, S Sernbo, E Andersson, DJ Brennan… - Molecular cancer, 2010 - Springer
Background The transcription factor SOX11 plays an important role in embryonic
development of the central nervous system (CNS) and is expressed in the adult immature
neuron but is normally not expressed in any other adult tissue. It has recently been reported
to be implicated in various malignant neoplasms, including several lymphoproliferative
diseases, by its specific expression and in some cases correlation to prognosis. SOX11 has
been shown to prevent gliomagenesis in vivo but the causes and consequences of aberrant …

[PDF][PDF] Research SOX11 expression correlates to promoter methylation and regulates tumor growth in hematopoietic malignancies

E Gustavsson, S Sernbo, E Andersson… - 2010 - molecular-cancer.biomedcentral …
Background: The transcription factor SOX11 plays an important role in embryonic
development of the central nervous system (CNS) and is expressed in the adult immature
neuron but is normally not expressed in any other adult tissue. It has recently been reported
to be implicated in various malignant neoplasms, including several lymphoproliferative
diseases, by its specific expression and in some cases correlation to prognosis. SOX11 has
been shown to prevent gliomagenesis in vivo but the causes and consequences of aberrant …
以上显示的是最相近的搜索结果。 查看全部搜索结果