Nucleic acid nanotechnology

H Yan - Science, 2004 - science.org
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Building programmable jigsaw puzzles with RNA

A Chworos, I Severcan, AY Koyfman, P Weinkam… - Science, 2004 - science.org
One challenge in supramolecular chemistry is the design of versatile, self-assembling
building blocks to attain total control of arrangement of matter at a molecular level. We have …

Directed DNA metallization

GA Burley, J Gierlich, MR Mofid, H Nir… - Journal of the …, 2006 - ACS Publications
Genes of interest can be selectively metallized via the incorporation of modified triphosphates.
These triphosphates bear functions that can be further derivatized with aldehyde groups …

Self-assembly of hexagonal DNA two-dimensional (2D) arrays

Y He, Y Chen, H Liu, AE Ribbe… - Journal of the American …, 2005 - ACS Publications
A three-point-star DNA motif has been designed and constructed, which can self-assemble
into hexagonal two-dimensional lattices. The resulting lattices are up to 1 mm. …

Symmetry controls the face geometry of DNA polyhedra

C Zhang, SH Ko, M Su, Y Leng, AE Ribbe… - Journal of the …, 2009 - ACS Publications
Two complementary strategies have been developed to control the face geometry during
the self-assembly of DNA polyhedra from branched DNA nanomotifs (tiles). In these …

Medication-related impulse control and repetitive behaviors in Parkinson disease

V Voon, SH Fox - Archives of neurology, 2007 - jamanetwork.com
A range of behaviors presumed to be related to aberrant or excessive dopaminergic medications
are being increasingly recognized in Parkinson disease. These behaviors are linked by …

Self-assembling a molecular pegboard

K Lund, Y Liu, S Lindsay, H Yan - Journal of the American …, 2005 - ACS Publications
This paper describes the design, construction, and application of a self-assembled, chemically
addressable DNA nanogrid composed of DNA tiles of nanometer dimensions. This self-…

Riboswitch structures: purine ligands replace tertiary contacts

A Lescoute, E Westhof - Chemistry & biology, 2005 - cell.com
Two recent reports describe the fascinating crystal structures of the G-riboswitch complexed
to three different purine ligands, hypoxanthine [1], guanine, and adenine [2]. …

Controlled spacing of cationic gold nanoparticles by nanocrown RNA

AY Koyfman, G Braun, S Magonov… - Journal of the …, 2005 - ACS Publications
Using atomic force microscopy, we describe the linear arrangement of cationic gold
nanoparticles directed by programmable self-assembling RNA ladders and demonstrate that the …

Co-transcriptional assembly of chemically modified RNA nanoparticles functionalized with siRNAs

KA Afonin, M Kireeva, WW Grabow, M Kashlev… - Nano …, 2012 - ACS Publications
We report a generalized methodology for the one-pot production of chemically modified
functional RNA nanoparticles during in vitro transcription with T7 RNA polymerase. The …