Search for evidence of a Th2 profile in HIV+ patients
MCG Galhardo, M Perez, MG Morgado… - International journal …, 2000 - Wiley Online Library
Background Hypersensitivity dermatoses are common in human immunodeficiency virus‐
positive (HIV+) patients, particularly as the disease progresses. Studies have shown that a
switch to T‐helper 2 (Th2) might represent a turning point in HIV. This study investigated
whether increases in the number of skin mast cells, immunoglobulin E (IgE) serum levels,
and eosinophilia, involved in the Th2 response in allergic disease, might also be present in
HIV+ patients. If so, these alterations might explain one of the mechanisms of skin …
positive (HIV+) patients, particularly as the disease progresses. Studies have shown that a
switch to T‐helper 2 (Th2) might represent a turning point in HIV. This study investigated
whether increases in the number of skin mast cells, immunoglobulin E (IgE) serum levels,
and eosinophilia, involved in the Th2 response in allergic disease, might also be present in
HIV+ patients. If so, these alterations might explain one of the mechanisms of skin …
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