… We found that pancreaticislets are innervated by vagal sensory axons expressing Phox2b, substance P, calcitonin-gene related peptide, and the serotonin receptor 5-HT 3 R. Centrally, …
RE Burris, M Hebrok - Neuroscience, 2007 - Elsevier
… Isletsensoryinnervation appears unaffected in RIP-cmyc ER … interruption of sensory innervation of pancreaticislets was … signaling takes place before pancreaticislets are fully mature, …
TH Lindsay, KG Halvorson, CM Peters, JR Ghilardi… - Neuroscience, 2006 - Elsevier
… nerve fibers immunostained for 200 kD neurofilament H (clone RT97) (A) are found near large blood vessels in the exocrine pancreas, but have minimal association with the islets of …
… branch out to innervate the vasculature, endocrine cells of pancreaticislets, exocrine acini, … sensory fibers project preferentially to pancreaticislets, indicating that the exocrine sensory …
B Thorens - Diabetes, Obesity and Metabolism, 2014 - Wiley Online Library
… secretion of glucagon and insulin by pancreaticislet α- and β-… nervous system that richly innervates this endocrine organ. … system, which richly innervatepancreaticislets to control many …
… content in the islets of Langerhans of thepancreas. These results … sensoryinnervation of pancreaticislets is key to regulating islet function and that a negative feedback loop of sensory …
… In addition to autonomic efferent axons, islets also receive sensoryinnervation. These … to stimulate specifically the axons innervatingthepancreaticislet. Stimulating the parasympathetic …
BA Lázár, G Jancsó, O Oszlács, I Nagy, P Sántha - Pancreas, 2018 - journals.lww.com
… , peptidergic primary sensory neurons … pancreatitis. Immunohistochemical studies have also revealed the coexpression of SP and CGRP with TRPV1 in sensorynerves serving the islets …
… By employing genetic and chemical ablation of sympathetic neurons in mice, we show that sympathetic innervation is necessary for establishing pancreaticislet shape and …