Leeway space and E-space plays a crucial role in the late transition phase from primary dentition to permanent dentition. Leeway space is normally 0.9 mm and 1.5 mm in upper and lower arch respectively. E-space is the difference in the mesiodistal width of deciduous second molar and permanent second premolar which is 2.3 in upper arch 2.5 mm in lower arch 1. E-space and leeway space are normally utilized by permanent first molars to establish class I molar relation in permanent dentition. We can also utilize this E-space during fixed orthodontic treatment for reliving of crowding in late mixed dentition. Thus, here in this article, we are presenting clinical technique along with case series of sequential utilization of E-space for correction of anterior crowding without extractions.