[HTML][HTML] Serum levels of IL-10 and IL-17A in occult HBV-infected South-East Iranian patients

MK Arababadi, AA Pourfathollah, A Jafarzadeh… - Hepatitis …, 2010 - ncbi.nlm.nih.gov
Hepatitis monthly, 2010ncbi.nlm.nih.gov
Results The results demonstrated that, 352 (9.5%) out of 3700 blood samples were HBsAg-
/anti-HBc+ and HBV-DNA was detected in 57/352 (16.1%) of the HBsAg-/anti-HBc+
samples. Our results showed that the IL-10 and IL-17A serum levels increased significantly
in the OBI cases in comparison to the controls (P< 0.001). Conclusions According to the
results of this study the higher level of IL-10 production may suppress the functioning of the
immune system against HBV in OBI patients. The elevated IL-17A serum level also indicates …
Results
The results demonstrated that, 352 (9.5%) out of 3700 blood samples were HBsAg-/anti-HBc+ and HBV-DNA was detected in 57/352 (16.1%) of the HBsAg-/anti-HBc+ samples. Our results showed that the IL-10 and IL-17A serum levels increased significantly in the OBI cases in comparison to the controls (P< 0.001).
Conclusions
According to the results of this study the higher level of IL-10 production may suppress the functioning of the immune system against HBV in OBI patients. The elevated IL-17A serum level also indicates a long period of infection in the patients observed.
ncbi.nlm.nih.gov
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