[HTML][HTML] Sex influences the frequency of the posterior basic alpha rhythm in patients with epilepsy

C Stephani, A Khan, M Koubeissi, W Paulus - Clinical Neurophysiology …, 2019 - Elsevier
Clinical Neurophysiology Practice, 2019Elsevier
Objective To determine effects of sex, epilepsy and epilepsy medication on the posterior
basic alpha rhythm. Methods We reviewed the routine EEGs of 160 subjects, including 60
individuals with focal epilepsy, 60 with generalized epilepsy, and 40 healthy controls,
measured the mean alpha frequencies of each person and applied a univariate three-
factorial analysis of variance. Results Women have a significantly faster posterior basic
rhythm as compared to men. Sex was the only independent factor influencing the posterior …
Objective
To determine effects of sex, epilepsy and epilepsy medication on the posterior basic alpha rhythm.
Methods
We reviewed the routine EEGs of 160 subjects, including 60 individuals with focal epilepsy, 60 with generalized epilepsy, and 40 healthy controls, measured the mean alpha frequencies of each person and applied a univariate three-factorial analysis of variance.
Results
Women have a significantly faster posterior basic rhythm as compared to men. Sex was the only independent factor influencing the posterior basic rhythm in this cohort. Additionally, we detected an interaction with intake of lamotrigine and idiopathic generalized epilepsy both increasing the basic alpha frequency in the group of female subjects only.
Conclusion
Sex was the main determinant of the posterior basic alpha frequency in our cohort.
Significance
Sex can influence the frequency of the posterior basic alpha rhythm.
Elsevier
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