This chapter has a form of a review article in the field of simulating High-Performance
Computing systems. We justify the need for a new versatile simulator considering
heterogeneity, energy efficiency and reliability of HPC systems. We sketch the problems that
need to be solved by such simulator and rationalize using discrete-event simulation for this
purpose. Based on a review of existing discrete-event HPC simulation solutions we propose
a flexible application execution model. Finally, we outline new directions of developing the …