In the past two decades, significant advances have been made in single-molecule detection
which enables the direct observation of single biomolecules at work in real time and under
physiological conditions. In particular, the development of single-molecule tracking (SMT)
microscopy allows us to monitor the motion paths of individual biomolecules in living
systems, unveiling the localization dynamics, and transport modalities of the biomolecules
that support the development of life. Beyond the capabilities of traditional camera-based …

There is a long list of people whom I am grateful to, but this section is only dedicated to those
who may actually read the following paragraphs. My acknowledgments will not make any
difference to the others anyway. I would like to thank the 2012 BME PhD students
recruitment committee. They picked up my resume from tons of applications, and gave me
an interview and an offer during the Spring Festival. Tim Yeh has been an amazing adviser
in many aspects. He has made an excellent demonstration of “how to survive as an assistant …