Skeletal muscle loss during aging leads to an increased risk of falls, fractures, and
eventually loss of independence. Resistance exercise is a useful intervention to prevent
sarcopenia; however, the muscle protein synthesis (MPS) response to resistance exercise is
less in elderly compared with young subjects. On the other hand, essential amino acids
(EAA) increase MPS equally in both young and old subjects when sufficient EAA is ingested.
We hypothesized that EAA ingestion following a bout of resistance exercise would stimulate …

The loss of skeletal muscle during aging (sarcopenia) leads to an increased risk of falls,
fractures and eventually loss of independence. Resistance exercise (RE) is a useful
intervention to prevent sarcopenia, however, the response to RE is less when compared to
young subjects. Essential amino acids (EAA) increase muscle protein synthesis (MPS)
equally in both young and old subjects. We hypothesized that EAA ingestion following RE
would restore anabolic signaling and MPS in aging muscle. Young and old men ingested …