… of hydrotropic solubilization and solubilization capacity of … measured the solubilization of
several poorly soluble drugs in … Figure 2 shows the solubilization data of five model drugs (…

… This article concludes that solubility of poorly water-soluble drugs is an important concept
to reach into systemic circulation to show its pharmacological response. Dissolution is a rate …

… decrease in the solubility of the active pharmaceutical ingredient. Therefore, the importance
of formulation strategies to improve the solubility of poorly water-soluble drugs is inevitable, …

… surfactant and drug molecular structures on drug solubility in … drug solubility parameters
used in oral absorption models. … on the solubilization of two poorly water-soluble drugs (…

… Solid dispersion is the most important method for improving of solubility of poorly water
soluble drugs. It also increases the bioavailability by physical modification. Solid dispersion …

… By conferring hydrophilicity to the hydrophobic drug particle surfaces, the added excipient
also enhances the wettability, solubility and bioavailability of the poorly water-soluble drug. …

… Thus, further advancements in solubility enhancement of poorly water-soluble drugs will
generate improved clinical benefits and great business potentials in pharmaceutical industry.. …

… poor water-solubility and the main strategies applied to increase the solubility of poorly
water-soluble drugs. … solubilization process of the drug is also considered. Finally, it includes how …

… for solubilization techniques are presented, and some approved poorly water-soluble drugs
using solubilization … in detail the solubilization mechanism of each solubilization technique, …

… Poor water solubility for many drugs and drug candidates … to improve solubility suffer
from low bioavailability and poor … for drug solubilization are presented. Strategies including …