Some desmoid tumors are characterized by trisomy 8
Genes, Chromosomes and Cancer, 1994•Wiley Online Library
Ten desmoid tumors were examined by chromosome banding analysis and by in situ
hybridization on short‐term cultures and frozen sections. Trisomy 8 was detected in four out
of ten tumors, of which only one had shown trisomy 8 by karyotype analysis. Since trisomy 8
has been reported in superficial fibromatoses, which are clinically distinct but histologically
similar to desmoid tumors, the occurrence of trisomy 8 in both may be a further indication of
a close relationship. Genes Chromosom Cancer 10: 131–135 (1994).© 1994 Wiley‐Liss …
hybridization on short‐term cultures and frozen sections. Trisomy 8 was detected in four out
of ten tumors, of which only one had shown trisomy 8 by karyotype analysis. Since trisomy 8
has been reported in superficial fibromatoses, which are clinically distinct but histologically
similar to desmoid tumors, the occurrence of trisomy 8 in both may be a further indication of
a close relationship. Genes Chromosom Cancer 10: 131–135 (1994).© 1994 Wiley‐Liss …
Abstract
Ten desmoid tumors were examined by chromosome banding analysis and by in situ hybridization on short‐term cultures and frozen sections. Trisomy 8 was detected in four out of ten tumors, of which only one had shown trisomy 8 by karyotype analysis. Since trisomy 8 has been reported in superficial fibromatoses, which are clinically distinct but histologically similar to desmoid tumors, the occurrence of trisomy 8 in both may be a further indication of a close relationship. Genes Chromosom Cancer 10:131–135 (1994). © 1994 Wiley‐Liss, Inc.
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