Sorbicillinoid-Based Metabolites from a Sponge-Derived Fungus Trichoderma saturnisporum

J Meng, W Cheng, H Heydari, B Wang, K Zhu… - Marine Drugs, 2018 - mdpi.com
Antibacterial activity assessment and high performance liquid chromatography associated
with nuclear magnetic resonance (HPLC/NMR) data revealed that the EtOAc extract of the
fermented endophytic fungus Trichoderma saturnisporum DI-IA, obtained from the marine
sponge Dictyonella incisa, contained conjugated olefinic metabolites with antibacterial
activity. Chemical examination of the fungal strain resulted in the isolation of eight new
sorbicillinoid-based compounds, namely saturnispols A–H (1–8). Their structures were …

Sorbicillinoid-Based Metabolites from a Sponge-Derived Fungus Trichoderma saturnisporum

H Heydari - dspace.ankara.edu.tr
Antibacterial activity assessment and high performance liquid chromatography associated
with nuclear magnetic resonance (HPLC/NMR) data revealed that the EtOAc extract of the
fermented endophytic fungus Trichoderma saturnisporum DI-IA, obtained from the marine
sponge Dictyonella incisa, contained conjugated olefinic metabolites with antibacterial
activity. Chemical examination of the fungal strain resulted in the isolation of eight new
sorbicillinoid-based compounds, namely saturnispols A⁻ H (1⁻ 8). Their structures were …
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