Specific V-ATPase expression sub-classifies IDHwt lower-grade gliomas and impacts glioma growth in vivo

A Terrasi, I Bertolini, C Martelli, G Gaudioso… - …, 2019 - thelancet.com
… We show that the expression of specific V-ATPase subunits by gliomas determines cancer …
, also in IDH-wild type lower-grade gliomas. The oncogenic V-ATPase profile associates with …

[PDF][PDF] Specific V-ATPase expression sub-classifies IDHwt lower-grade gliomas and impacts glioma growth in vivo

T Vaccari, V Vaira - 2019 - air.unimi.it
… We show that the expression of specific V-ATPase subunits by gliomas determines cancer …
, also in IDH-wild type lower-grade gliomas. The oncogenic V-ATPase profile associates with …

V-ATPase Sub-Classifies IDHwt Lowergrade Gliomas and Directs Extracellular Signaling Through Large Oncosomes and Homeobox Genes

I Bertolini, A Terrasi, C Martelli, G Gaudioso… - 2018 - papers.ssrn.com
… that VATPase subunit expression correlates with gliomaglioblastoma (GBM) and relapsed
gliomas display a specificlower grade gliomas (LGG) are characterized by expression of …

Identification of a five-gene signature deriving from the vacuolar ATPase (V-ATPase) sub-classifies gliomas and decides prognoses and immune microenvironment …

C Qi, L Lei, J Hu, G Wang, J Liu, S Ou - Cell Cycle, 2022 - Taylor & Francis
… of subunits of the V-ATPase in glioma patients, we … lower-grade gliomas. Another study
from Couta-Viera and colleagues suggested that a differential expression pattern of V-ATPase

V-ATPase expression in gliomas—Not your grandparents' proton pump

M Graner - EBioMedicine, 2019 - thelancet.com
Specific v-atpase expression sub-classifies idhwt lower-grade gliomas and impacts
glioma growth in vivo. EBioMedicine 2019. https://doi.org/10.1016/j.ebiom.2019.01.052. …

Further insight into V-ATPase role in glioma stem cells

A Storaci - 2020 - tesidottorato.depositolegale.it
Specific V-ATPase expression sub-classifies IDHwt lowergrade gliomas and impacts
glioma growth in vivo. EBioMedicine 2019;41:214–24. doi:10.1016/j.ebiom.2019.01.052. …

V-ATPASE AND AUTOPHAGY PREVENT GLIOMA GROWTH IN A DROSOPHILA MODEL SYSTEM

M Formica - 2019 - tesidottorato.depositolegale.it
… tend to evolve from a lower grade astrocytoma and generally they … that V-ATPase shows a
specific expression pattern. Thus, the … to study the effect of V-ATPase activity in tumorigenesis. …

[HTML][HTML] V-ATPase in glioma stem cells: a novel metabolic vulnerability

AM Storaci, I Bertolini, C Martelli… - … of Experimental & …, 2025 - jeccr.biomedcentral.com
… Because of the pleiotropic effects of V-ATPase activity, this pump … the V-ATPase pump are
expressed in low-grade glioma respect to GBM and that the pump conformation affects glioma

Vacuolar Proton-Translocating ATPase May Take Part in the Drug Resistance Phenotype of Glioma Stem Cells

M Giambra, A Di Cristofori, F Raimondo… - International Journal of …, 2024 - mdpi.com
… to analyze the effects of V-ATPase inhibition by bafilomycin … role of Baf on V-ATPase protein
expression, we assessed … of the V-ATPase proton pump was investigated using a specific

A GBM-like V-ATPase signature directs cell-cell tumor signaling and reprogramming via large oncosomes

I Bertolini, A Terrasi, C Martelli, G Gaudioso… - …, 2019 - thelancet.com
… investigated how expression of a GBM-like V-ATPase pump … of homeobox genes were
specific for V-ATPase activity or … glioma patients, we were able to sort out IDHwt lower-grade