Specular microscopy is a noninvasive diagnostic tool that allows for in vivo evaluation of
corneal endothelium in health and various diseased states. Endothelial imaging helps in the
diagnosis and management of several endothelial disorders. The review focuses on the
principles of specular microscopy, limitations of endothelial imaging, and its interpretation in
common conditions seen in the clinical practice. A thorough PubMed search was done using
the keywords specular microscopy, corneal endothelium, and endothelial imaging.