Squamous cell carcinoma with aggressive subclinical extension: 5-year retrospective review of diagnostic predictors
A Goldenberg, A Ortiz, SS Kim, SB Jiang - Journal of the American …, 2015 - Elsevier
Background Squamous cell carcinoma with aggressive subclinical extension (SCC-ASE) is
a tumor whose extensive spread becomes revealed during surgery or pathologic review,
particularly during Mohs micrographic surgery. Limited clinical awareness of these lesions
may result in unanticipated longer surgical times and larger postoperative defects. SCC-ASE–
associated clinical risk factors are not well studied. Objective We sought to evaluate the
incidence of and risk factors associated with SCC-ASE. Methods We conducted a …
a tumor whose extensive spread becomes revealed during surgery or pathologic review,
particularly during Mohs micrographic surgery. Limited clinical awareness of these lesions
may result in unanticipated longer surgical times and larger postoperative defects. SCC-ASE–
associated clinical risk factors are not well studied. Objective We sought to evaluate the
incidence of and risk factors associated with SCC-ASE. Methods We conducted a …
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