appreciation for the role of specific metabolic pathways in dictating cell fate. Once thought to
be a mere consequence of the state of a cell, metabolism is now known to play a pivotal role
in dictating whether a cell proliferates, differentiates or remains quiescent. Here, we review
recent studies of metabolism in stem cells that have revealed a shift in the balance between
glycolysis, mitochondrial oxidative phosphorylation and oxidative stress during the …