Steroid hormone modulates the production of cathelicidin and human β-defensins in lung epithelial cells and macrophages promoting Mycobacterium tuberculosis …
SP Marin-Luevano, A Rodriguez-Carlos… - Tuberculosis, 2021 - Elsevier
Several studies have documented the interaction between the immune and endocrine
systems as an effective defense strategy against tuberculosis, involving the production of
several molecules and immunological processes. In this study, we determined the effect of
cortisol and dehydroepiandrosterone (DHEA) on the production of antimicrobial peptides
such as cathelicidin and human β-defensin (HBD)− 2, and HBD-3 and their effect on
intracellular growth of Mycobacterium tuberculosis (Mtb) in lung epithelial cells and …
systems as an effective defense strategy against tuberculosis, involving the production of
several molecules and immunological processes. In this study, we determined the effect of
cortisol and dehydroepiandrosterone (DHEA) on the production of antimicrobial peptides
such as cathelicidin and human β-defensin (HBD)− 2, and HBD-3 and their effect on
intracellular growth of Mycobacterium tuberculosis (Mtb) in lung epithelial cells and …
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