Strategies to broaden the cross-protective efficacy of vaccines against porcine reproductive and respiratory syndrome virus

HLX Vu, AK Pattnaik, FA Osorio - Veterinary microbiology, 2017 - Elsevier
Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most
economically important viral pathogens currently affecting swine production worldwide.
Although PRRS vaccines have been commercially available for over 20 years, the available
vaccines are considered inadequately effective for control and eradication of the virus. Major
obstacles for the development of a highly effective PRRS vaccine include the highly variable
nature of the viral genome, the viral ability to subvert the host immune system, and the …
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