The plasma membrane forms the physical barrier between the cytoplasm and extracellular
space, allowing for biochemical reactions necessary for life to occur. Plasma membrane
damage needs to be rapidly repaired to avoid cell death. This relies upon the coordinated
action of the machinery that polarizes the repair response to the site of injury, resulting in
resealing of the damaged membrane and subsequent remodeling to return the injured
plasma membrane to its pre-injury state. As lipids comprise the bulk of the plasma …