This study aims to provide an overview of the communication and interaction skills of students in terms of major and gender groups. This research was conducted using survey methods at the UniversitasNegeri Medan (UNIMED). Student samples totaling 400 people were determined by purposive random sampling technique. Communication and interaction skillsdata are captured using a questionnaire with a Likert scale model with a reliability coefficient of 0.726. Research findings are:(1) Communication and interaction skills of students tend to be in the medium category;(2) Students' communication and interaction skills can be influenced by major groups (natural science or social science) and gender.