In this paper, the performance of (CuI/CH3NH3PbI3-xClx/ZnO/TCO) Perovskite solar cell (PSC) is studied using Solar Cell Capacitance Simulator (SCAPS-1D). In this solar cell structure, the absorber layer CH3NH3PbI3-xClx characterized by a highly efficient absorption, the CuI layer is used as a hole transporter material (HTM), and ZnO layer is used as an electron transporter material (ETM). They exhibit a good chemical stability and low cost of synthesis procedure compared with conventional layers 2,2',7,7'-Tetrakis [N,N-di(4-methoxyphenyl)amino]-9,9'-spirobifluorene (Spiro-OMETAD) and Phenyl-C61-butyric acid methyl ester (PCBM). The optimum configuration is obtained by varying the thickness of different layers, and the simulation results of the investigated PSC exhibit Voc = 1.256 V, Jsc = 25.06 mA/Cm2, FF = 80.67 % and a conversion efficiency of 25.40 %. The results are very promising and the proposed configuration performs better; it can be also considered as a good candidate for developing cheaper and efficient PSCs.