B Hui, W Xia, J Li, L Wang, J Ai… - Journal of …, 2006 - Wiley Online Library
… of severe CNS disorders classified as the human immunodeficiency virus-1 … sulfated polymannuroguluronate (SPMG), a novelanti-acquiredimmunodeficiencysyndromedrugcandidate …
B Hui, J Li, MY Geng - Journal of neuroscience research, 2008 - Wiley Online Library
… We herein report that sulfatedpolymannuroguluronate (SPMG), a novelanti-acquired immunodeficiencysyndromedrugcandidate now in phase II clinical trial, significantly decreased …
… , an angioproliferation disease, is a form of malignancy which occurs in elderly or immunosuppressed patients, and is often associated with acquiredimmunedeficiencysyndrome …
MBC Miao BenChun, GMY Geng MeiYu, LJ Li Jing… - 2004 - cabidigitallibrary.org
… Sulfatedpolymannuroguluronate (SPMG), a marine sulfated polysaccharide extracted from … as the first anti-acquiredimmunedeficiencysyndrome (AIDS) drugcandidate obtained from …
… Therefore, it is essential to isolate novelanti-HIV therapeutics … a novelcandidate for the development of anti-HIV-1 agents. … of marine sulfatedpolymannuroguluronate interfering with HIV…
W Xia, J Li, M Geng, X Xin, J Ding - Journal of pharmacological …, 2005 - jstage.jst.go.jp
… immunodeficiency virus (SIV) (6). SPMG has been approved as an anti-acquiredimmune deficiencysyndrome (AIDS) candidate, … The mechanisms of action underlying the anti-HIV-1 …
Y Wu, J Ai, J Zhao, B Xiong, X Xin, M Geng… - Acta Pharmacologica …, 2011 - nature.com
… Sulfatedpolymannuroguluronate (SPMG), a candidateanti-AIDS drug, inhibited HIV replication and interfered with HIV entry into host T lymphocytes. SPMG has high binding affinity for …
C Hao, G Yu, Y He, C Xu, L Zhang… - Reviews in medical …, 2019 - Wiley Online Library
… .24, 25 In addition, sulfatedpolymannuroguluronate (SPMG), a … great potential to be developed into novel antiviral drugs. … -515) may be a novelanti-HIV candidate with low toxicity and …
B Miao, J Li, X Fu, J Ding, M Geng - International immunopharmacology, 2005 - Elsevier
… Sulfatedpolymannuroguluronate (SPMG) has entered the Phase II clinical trial as the first anti-acquiredimmunedeficiencysyndrome (AIDS) drugcandidate in China. Proliferation …