Suppression of prostate carcinogenesis by dietary supplementation of celecoxib in transgenic adenocarcinoma of the mouse prostate model

S Gupta, VM Adhami, M Subbarayan, GT MacLennan… - Cancer research, 2004 - AACR
Epidemiological studies and clinical observations suggest that nonsteroidal anti-
inflammatory drugs and certain selective cyclooxygenase (COX)-2 inhibitors may reduce the
relative risk of clinically evident prostate cancer. This prompted us to investigate the
chemopreventive potential of celecoxib, a selective COX-2 inhibitor, against prostate
carcinogenesis in a transgenic adenocarcinoma of the mouse prostate (TRAMP) model.
Similar to prostate cancer in humans, prostate malignancies in TRAMP mice progress from …

[引用][C] Suppression of Prostate Carcinogenesis by Dietary Supplementation of Celecoxib in Transgenic Adenocarcinoma of the Mouse Prostate Model

TL Ratliff - The Journal of Urology, 2004 - auajournals.org
Suppression of Prostate Carcinogenesis by Dietary Supplementation of Celecoxib in
Transgenic Adenocarcinoma of the Mouse Prostate Model | Journal of Urology …
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