[HTML][HTML] Survival in sensitized lung transplant recipients with perioperative desensitization
KJ Tinckam, S Keshavjee, C Chaparro, D Barth… - American Journal of …, 2015 - Elsevier
Donor-specific HLA antibodies (DSA) have an adverse effect on short-term and long-term
lung transplant outcomes. We implemented a perioperative strategy to treat DSA-positive
recipients, leading to equivalent rejection and graft survival outcomes. Pretransplant DSA
were identified to HLA-A, B, C, DR and DQ antigens. DSA-positive patients were
transplanted if panel reactive antibody (PRA)≥ 30% or medically urgent and desensitized
with perioperative plasma exchange, intravenous immune globulin, antithymocyte globulin …
lung transplant outcomes. We implemented a perioperative strategy to treat DSA-positive
recipients, leading to equivalent rejection and graft survival outcomes. Pretransplant DSA
were identified to HLA-A, B, C, DR and DQ antigens. DSA-positive patients were
transplanted if panel reactive antibody (PRA)≥ 30% or medically urgent and desensitized
with perioperative plasma exchange, intravenous immune globulin, antithymocyte globulin …
以上显示的是最相近的搜索结果。 查看全部搜索结果