[PDF][PDF] Synthesis, spectral and biological studies of thiazole Schiff base derived from 4-(2'-fluorophenyl)-2-aminothiazole

S Rajmane, VP Ubale, LB Dama, MR Asabe… - International Journal of …, 2013 - ijpsi.org
S Rajmane, VP Ubale, LB Dama, MR Asabe, PG More
International Journal of Pharmaceutical Science Invention, 2013ijpsi.org
A Schiff base ligand has been synthesized by reacting 4-(2'-fluorophenyl)-2-aminothiazole
and 2-hydroxynaphthaldehyde. The ligand was characterized by elemental, spectral and
XRD analysis. The ligand was evaluated for their in vitro nematicidal and molluscicidal
activities. It is active in very low concentration on plant parasitic nematode Meloidogyne
javanica and freshwater helminthiasis vector snail Lymnea auricularia. X-ray diffraction
studies suggested a triclinic crystal system for the ligand.
Abstract
A Schiff base ligand has been synthesized by reacting 4-(2’-fluorophenyl)-2-aminothiazole and 2-hydroxynaphthaldehyde. The ligand was characterized by elemental, spectral and XRD analysis. The ligand was evaluated for their in vitro nematicidal and molluscicidal activities. It is active in very low concentration on plant parasitic nematode Meloidogyne javanica and freshwater helminthiasis vector snail Lymnea auricularia. X-ray diffraction studies suggested a triclinic crystal system for the ligand.
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