Systemic RNAi in western corn rootworm, Diabrotica virgifera virgifera, does not involve transitive pathways

H Li, AJ Bowling, P Gandra, M Rangasamy… - Insect …, 2018 - Wiley Online Library
Western corn rootworm (WCR, Diabrotica virgifera virgifera LeConte) is highly sensitive to
orally delivered double‐stranded RNA (dsRNA). RNAi in WCR is systemic and spreads
throughout the insect body. This raises the question whether transitive RNAi is a mechanism
that functions in WCR to amplify the RNAi response via production of secondary siRNA.
Secondary siRNA production is achieved through RNA‐dependent RNA polymerase
(RdRP) activity in other eukaryotic organisms, but RdRP has not been identified in WCR and …

Systemic RNAi in western corn rootworm, Diabrotica virgifera virgifera, does not involve transitive pathways.

LHR Li HuaRong, AJ Bowling, P Gandra… - 2018 - cabidigitallibrary.org
Western corn rootworm (WCR, Diabrotica virgifera virgifera LeConte) is highly sensitive to
orally delivered double-stranded RNA (dsRNA). RNAi in WCR is systemic and spreads
throughout the insect body. This raises the question whether transitive RNAi is a mechanism
that functions in WCR to amplify the RNAi response via production of secondary siRNA.
Secondary siRNA production is achieved through RNA-dependent RNA polymerase (RdRP)
activity in other eukaryotic organisms, but RdRP has not been identified in WCR and any …
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