TSLP elicits IL-33independent innate lymphoid cell responses to promote skin inflammation

BS Kim, MC Siracusa, SA Saenz, M Noti… - Science translational …, 2013 - science.org
TSLP-elicited group 2 ILCs can function independently of IL-33 and IL-25 to promote AD-like
inflammation… ILCs directly or indirectly promote AD-like inflammation remain to be elucidated…

Intelectin contributes to allergen-induced IL-25, IL-33, and TSLP expression and type 2 response in asthma and atopic dermatitis

L Yi, D Cheng, K Zhang, X Huo, Y Mo, H Shi, H Di… - Mucosal …, 2017 - nature.com
IL-33, and TSLP can stimulate group 2 innate lymphoid cellsinflammation to examine the
kinetics of Itln1, Il-25, Il-33, and … Itln after parasite infection is independent of adaptive immunity. …

[HTML][HTML] IL-17A–Producing innate lymphoid cells promote skin inflammation by inducing IL-33–driven type 2 immune responses

MH Kim, SP Jin, S Jang, JY Choi, DH Chung… - Journal of Investigative …, 2020 - Elsevier
innate cytokines such as Il33 and Tslp, which induce type 2 immune responses, was higher
in AD skin than in control skin… Data were obtained from two independent experiments (n = 4–…

Innate lymphoid cells and allergic inflammation

BS Kim, EDT Wojno, D Artis - Current opinion in immunology, 2013 - Elsevier
… of CD4 + T H 2 cell responses, antigen-specific IgE … they are optimally elicited by IL-25
rather than IL-33 and exhibit a … , lung, and skin, produce the cytokines IL-25, IL-33, and TSLP or …

Role of IL‐25, IL33, and TSLP in triggering united airway diseases toward type 2 inflammation

H Hong, S Liao, F Chen, Q Yang, DY Wang - Allergy, 2020 - Wiley Online Library
… Although independent of caspase-1 cleavage, the full length … In the lower airway, the distinct
increase in IL-33 is also … cytokines, are all triggers to elicit TSLP production, whereas IFN-γ …

Basophils promote innate lymphoid cell responses in inflamed skin

BS Kim, K Wang, MC Siracusa, SA Saenz… - The Journal of …, 2014 - journals.aai.org
… Data are representative of two independent experiments; n = … TSLP-elicited basophils
promote local Th2 cell responses in … cell–derived cytokines such as IL-25, IL-33, and TSLP (3), or …

Combinatorial targeting of TSLP, IL-25, and IL-33 in type 2 cytokine–driven inflammation and fibrosis

KM Vannella, TR Ramalingam, LA Borthwick… - Science translational …, 2016 - science.org
… IL-13–producing type 2 innate lymphoid cells (ILC2s) were … T helper 2 (T H 2) cell responses,
but only in the presence of … lungs and liver independently of TSLP, IL-25, and IL-33. We did, …

Interleukin-33 in atopic dermatitis

Y Imai - Journal of dermatological science, 2019 - Elsevier
… of IL-33-induced AD and human clinical trials of anti-IL-33innate immunity, can activate
group 2 innate lymphoid cells (… to produce type2 cytokines by IL-33, not by TSLP or IL-25 [18]. …

IL-33 promotes the induction and maintenance of Th2 immune responses by enhancing the function of OX40 ligand

N Murakami-Satsutani, T Ito, T Nakanishi… - Allergology …, 2014 - jstage.jst.go.jp
cells,26 and group 2 innate lymphoid cells.Indeed, increased … 3 Effect of IL-33 on TSLP-DC-mediated
Th2 cell responses. … of the responses elicited by IL-33, which might pathophysi…

[HTML][HTML] IL-33 promotes gastrointestinal allergy in a TSLP-independent manner

H Han, F Roan, LK Johnston, DE Smith, PJ Bryce… - Mucosal …, 2018 - Elsevier
… that local delivery of IL-33 is sufficient to drive inflammation in the skin. Recombinant …
Challenge with OVA following skin administration of IL-33+OVA elicited a robust pattern of …