Vascular inflammation is a common, complex mechanism involved in pathogenesis of a
plethora of disease conditions including ischemia–reperfusion, atherosclerosis, restenosis
and stroke. Specific targeting of imaging probes and drugs to endothelial cells in
inflammation sites holds promise to improve management of these conditions. Nanocarriers
of diverse compositions and geometries, targeted with ligands to endothelial adhesion
molecules exposed in inflammation foci are devised for this goal. Imaging modalities that …