diagnostic purposes. The classification of leptospires has undergone several changes
following the discovery of the leptospirosis agent more than a century ago. With the genomic
era, the number of described Leptospira species has more than doubled in recent years.
Genotyping, including whole-genome-based typing, allows discrimination of isolates at the
subspecies level. Access to genomes has also facilitated the study of gene repertoire and …