Telechelic polymers from reversible-deactivation radical polymerization for biomedical applications

D Vinciguerra, J Tran, J Nicolas - Chemical Communications, 2018 - pubs.rsc.org
Chemical Communications, 2018pubs.rsc.org
… They can be either homotelechelic (same functionality at both chain-ends) or
heterotelechelic (different chain-ends), also called heterobifunctional polymers (Fig. 1a). A
convenient way to prepare telechelic polymers relies on the use of reversible-deactivation
radical polymerization (RDRP), such as nitroxide-mediated radical polymerization (NMP),
12 atom-transfer radical polymerization (ATRP) 13 or reversible addition–fragmentation
chain transfer (RAFT) polymerization. Not only do these polymerization techniques allow …
The main strategies for the design of telechelic polymers synthesized by reversible-activation radical polymerization for biomedical applications are covered spanning from drug delivery and targeting to theranostics and sensing.
The Royal Society of Chemistry
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