Discussion

Long-term sequelae are reported among EVD survivors. Recently, at the 2016 American Academy of Neurology Annual Meeting, Lauren Bowen referred to long-lasting neurological sequelae after EBOV infection, including weakness, headache, memory loss, depressed mood, muscle pain, tremors, abnormal eye movements and irregular reflexes. 3 No EVD case reporting neurocognitive impairment during the acute phase of the infection has been published. During the early EVD phase, the two reported cases showed a mild reactive deficit in memory tasks, which quickly disappeared during follow-up. They had no permanent cognitive disorders and they fully recovered. EVD-associated symptoms were not present at baseline and follow-up and were unlike to have directly influenced the neurocognitive performance. No neurological imaging was performed, considering the need to minimise EBOV exposure risks in the presence of mild deficits.