… hypothesis of no difference no longer apply. This paper reviews some of the test statistics
and sample size formulae proposed for comparative binomial trials when the null hypothesis is …

… This paper reports the results of an extensive empirical investigation comparing the well …
‘Test statistics and sample size formulae for comparative binomial trials with null hypothesis …

… If y ij follows a negative binomial distribution with a mean μ ij and a common dispersion …
between treatment groups under the alternative hypothesis will require a larger sample size. …

… the null power function (ie, under the null hypothesis) of a test … x 2 BINOMIAL TRIAL In
comparing two binomial proportions … the conditional test and formulae for the large sample tests. …

… on sample size calculations. The importance of a sample size calculation when designing a
clinical trial is … that they are set a priori when considering the null and alternative hypotheses. …

… In superiority trials often the null hypothesis will be convex, … the calculation of the maximum
to the boundary of the null … We have not addressed sample size issues for the exact LR-test in …

… approaches to calculation of sample size for controlled trials. It then … of the test statistic under
both the null hypothesis and the … A comparison of some methods of sample size calculation …

… (5.99), we cannot reject the null hypothesis of p = 0.6 and 0 = … sample size for the variable
following a Binomial distribution … equation can be used both for determination of sample size …

… Choices of Test Statistics In this section, we discuss four test statistics that can be used to …
Test statistics and sample size formulae for comparative binomial trials with null hypothesis …

… Attention is confined to the case where the null hypothesis is true. The dependence ofthe
tests on m and n,the sample sizes, and on P, the common binomial parameter, is investigated. …