Recursive combination tests

W Brannath, M Posch, P Bauer - Journal of the American Statistical …, 2002 - Taylor & Francis
R be increasing in both arguments and strictly increasing in at least one argument.
Without loss of generality, we assume that C40105D0 and C41115D1. Let 0µ 1 <0 µ1 be …

Design and analysis of drug combination experiments

R Straetemans, T O'Brien, L Wouters… - … Journal: Journal of …, 2005 - Wiley Online Library
… 50%), Ca, r and Cb, r are the … a combination of the two drugs and ICX, a and ICX, b are the
concentration of drug A and B yielding the same effect level, when administered alone, as the

[图书][B] The R book

MJ Crawley - 2012 - books.google.com
… ‘…if you are an R user or wannabe R user, this text is the one that should be on your shelf.
The breadth of topics covered is unsurpassed when it comes to texts on data analysis in R.’ …

Interaction index and different methods for determining drug interaction in combination therapy

JJ Lee, M Kong, GD Ayers, R Lotan - Journal of biopharmaceutical …, 2007 - Taylor & Francis
… We also provide S-PLUS/R code for each approach to facilitate the … we expect that the
combination dose (d 1 , d 2 ) will have the same … under the Loewe additivity model but not the Bliss …

[PDF][PDF] Is an “à la carte” combination interferon alfa‐2b plus ribavirin regimen possible for the first line treatment in patients with chronic hepatitis C?

T Poynard, J McHutchison, Z Goodman, MH Ling… - …, 2000 - Wiley Online Library
… for IFN-R in comparison with IFN alone whatever the combination of factors. The most efficient
… In conclusion, combination IFN-R is the new first line treatment for chronic hepatitis C. …

A generalized theory of the combination of observations so as to obtain the best result

S Newcomb - American journal of Mathematics, 1886 - JSTOR
… , which tern signifies such a magnitude that the number of errors less than r in absolute value
is … number which exceed r. The value of r is given in terms of the modulus h by the equation …

DRUG RESISTANCE OF ENTERIC BACTERIA IV: Active Transducing Bacteriophage P1 CM Produced by the Combination of R Factor With Bacteriophage P1

E Kondo, S Mitsuhashi - Journal of Bacteriology, 1964 - Am Soc Microbiol
… to the host bacteria was enhanced by thethe ability to transduce the CMr character but
also the capacity to form plaques; ie, the CMr gene of R factor is specifically associated with the

Efficient production of 22(R)‐hydroxycholesterol via combination optimization of Saccharomyces cerevisiae

Y Pang, X Cheng, Y Ban, Y Li, B Lv… - Biotechnology …, 2024 - Wiley Online Library
… In this study, heterologous enzymes Dhcr7s and cholesterol 22-hydroxylases from diverse
sources were evaluated to identify the optimal combination for 22(R)-HCHO production. …

… -stage follicular lymphoma treated front-line with rituximab and the combination of cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) with respect …

C Buske, E Hoster, M Dreyling, J Hasford, M Unterhalt… - Blood, 2006 - ashpublications.org
… In order to evaluate the predictive value of the FLIPI in terms of treatment … the conditions
of an R-chemotherapy combination, we analyzed a patient cohort of the prospective trial by the

The combination of estimates from different experiments

WG Cochran - Biometrics, 1954 - JSTOR
… account the purpose for which the combined estimate is to be made and the reasons for the
… For example, if xi is an unweighted mean over r replications, f = r, and if xi is the difference …