established as a valuable source for drug discovery and biotechnology but is
underrepresented within accessible genome and strain collections. Herein, we introduce the
Natural Products Discovery Center (NPDC), featuring 122,449 strains assembled over eight
decades, the genomes of the first 8490 NPDC strains (7142 Actinobacteria), and the online
NPDC Portal making both strains and genomes publicly available. A comparative survey of …