The OECD program to validate the rat uterotrophic bioassay. Phase 2: dose-response studies.
J Kanno, L Onyon, S Peddada, J Ashby… - Environmental …, 2003 - ehp.niehs.nih.gov
The Organisation for Economic Co-operation and Development has completed phase 2 of
an international validation program for the rodent uterotrophic bioassay. The purpose of the
validation program was to demonstrate the performance of two versions of the uterotrophic
bioassay, the immature female rat and the adult ovariectomized rat, in four standardized
protocols. This article reports the dose-response studies of the validation program; the
coded single-dose studies are reported in an accompanying paper. The dose-response …
an international validation program for the rodent uterotrophic bioassay. The purpose of the
validation program was to demonstrate the performance of two versions of the uterotrophic
bioassay, the immature female rat and the adult ovariectomized rat, in four standardized
protocols. This article reports the dose-response studies of the validation program; the
coded single-dose studies are reported in an accompanying paper. The dose-response …