ligase in both plants and animals. In dark-grown Arabidopsis thaliana seedlings, COP1
targets photomorphogenesis-promoting factors for degradation to repress
photomorphogenesis. Little is known, however, about how COP1 itself is regulated. Here,
we identify COP1 SUPPRESSOR1 (CSU1), a RING-finger E3 ubiquitin ligase, as a regulator
of COP1. Genetic evidence demonstrates that csu1 mutations suppress cop1-6 phenotypes …