We briefly present the principal properties of THGEM detectors, in standard and in noble gases (Xe, Kr, Ar and Ne), and shortly discuss their potential applications in accelerator- and non-accelerator-based experiments. UV-photon imaging in RICH, tracking of ionizing particles, large-volume TPCs for rare-events, sampling elements in digital calorimetry, ionization and scintillation recording from noble-liquid detectors, X-ray and neutron radiography etc.